Effectiveness Of Non-Nutritive Sucking and Murottal In Reducing Neonates' Pain Response To Needle-Related Medical Procedures
Keywords:
Non-Nutritive Sucking Murottal Neonatepain response medical procedures needle
Abstract
Neonates are newborns up to 28 days old who are highly vulnerable to infections and organ system disorders, often requiring medical intervention. One of the most common medical procedures performed on neonates is needle-related invasive procedures, such as intravenous catheter insertion and blood sampling, which can cause pain. Neonatal pain management generally avoids the use of pharmacological analgesics due to their various side effects. Therefore, effective non-pharmacological methods, such as Non-Nutritive Sucking (NNS) and Murottal therapy, are needed. This study aims to determine the effects of NNS, Murottal therapy, and their combination on reducing neonatal pain responses during needle-related medical procedures, using a quasi-experimental post-test only control group design. This study was conducted at Lamaddukelleng District General Hospital, Wajo Regency, South Sulawesi, specifically in the perinatology ward from August to October 2024 with a sample size of 92 people. The results indicate that the combination of NNS and Murottal therapy is the most effective in reducing neonatal pain responses during needle-related medical procedures, with an average pain response of 3.78 and a significance value of P > 0.001, compared to neonates who received a single intervention (either NNS or Murottal) or those in the control group.
References
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Qiu, J., Jiang, Y., Li, F., Tong, Q., Rong, H., & Cheng, R. (2017). Effect of combined music and touch intervention on pain response and β-endorphin and cortisol concentrations in late preterm infants. BMC Pediatrics, 17. https://doi.org/10.1186/s12887-016-0755-y
Shah, S. R., Kadage, S., & Sinn, J. (2017). Trial of Music, Sucrose, and Combination Therapy for Pain Relief during Heel Prick Procedures in Neonates. The Journal of Pediatrics, 190, 153-158.e2. https://doi.org/10.1016/j.jpeds.2017.08.003
Asadi-Noghabi, F., Tavassoli-Farahi, M., Yousefi, H., & Sadeghi, T. (2014). Neonate Pain Management: What do Nurses Really Know? Global Journal of Health Science, 6(5).
https://doi.org/10.5539/gjhs.v6n5p284
Krishnan, L. (2013). Pain Relief in Neonates. Journal of Neonatal Surgery, 2(2), 19. https://doi.org/10.47338/jns.v2.31
Thiviya Selvanathan, Ufkes, S., Guo, T., Chau, V., Branson, H. M., Ibrahim, G. M., Ly, L. G., Kelly, E. N., Grunau, R. E., & Miller, S. P. (2024). Pain Exposure
and Brain Connectivity in Preterm Infants. JAMA Network Open, 7(3), e242551–e242551. https://doi.org/10.1001/jamanetworkopen.2024.2551
Campbell, T. S., Johnson, J. A., & Zernicke, K. A. (2020). Gate control theory of pain. Encyclopedia of Behavioral Medicine, 1(1), 914–916. https://doi.org/10.1007/978-3-030-39903-0_113
Badan Pusat Statistik Indonesia. (2023). Laporan Survei Demografi dan Kesehatan Indonesia - Tabel Statistik. Bps.go.id; Badan Pusat Statistik Indonesia.https://www.bps.go.id/id/statistics-table/1/MjExMSMx/laporan-survei-
demografi-dan-kesehatan-indonesia.html
World Health Organization. (2024, March 14). Newborn mortality.
Mariyam, M., Hidayati, I. N., & Alfiyanti, D. (2019). Knowledge and Attitudes of Nurses About Pain Management in Neonates in the Perinatology Room and PICU / NICU. Media Keperawatan Indonesia, 2(2), 19. https://doi.org/10.26714/mki.2.2.2019.19-24
Lim, Y., & Godambe, S. (2017). Prevention and management of procedural pain in the neonate: an update, American Academy of Pediatrics, 2016. Archives of Disease in Childhood - Education & Practice Edition, 102(5), 254–256. https://doi.org/10.1136/archdischild-2016-311066
Wilujeng, A. P., & Suryaningsih, I. (2021). Pengaruh Non Nutritive Sucking Terhadap Nyeri Selama Prosedur Invasif Pada Neonatus. Jurnal Ilmu Kesehatan, 10(1), 65. https://doi.org/10.32831/jik.v10i1.371
Vu-Ngoc et al,. (2020). Analgesic effect of non-nutritive sucking in term neonates: A randomized controlled trial. Pediatrics & Neonatology, 61(1), 106–113. https://doi.org/10.1016/j.pedneo.2019.07.003
Wahida Azis, Muhammad Nooryanto, & Sri Andarini. (2015). Terapi Murotal Al-Qur’an Surat Arrahman Meningkatkan Kadar Î2-Endorphin dan Menurunkan Intensitas Nyeri pada Ibu Bersalin Kala I Fase Aktif. Jurnal Kedokteran Brawijaya (E-Journal), 28(3), 213–216. https://doi.org/10.21776/ub.jkb.2015.028.03.9
Harrison, D., & Bueno, M. (2023). Translating evidence: pain treatment in newborns, infants, and toddlers during needle-related procedures. PAIN Reports, 8(2), 1–8. https://doi.org/10.1097/pr9.0000000000001064
Wilson-Smith, E. M. (2011). Procedural Pain Management in Neonates, Infants
and Children. Reviews in Pain, 5(3), 4–12. https://doi.org/10.1177/204946371100500303
Bahrudin, M. (2018). Patofisiologi Nyeri (Pain). Saintika Medika, 13(1), 7. https://doi.org/10.22219/sm.v13i1.5449
Nengrum, L. S., & Istiqomah, M. (2024). Efektifitas Pemberian Non Nutritive Sucking Terhadap Respon Nyeri Neonatus Pada Pemberian Imunisasi Hb0 Diruang Perinatologi Rs X Husada Malang. Borneo Journal of Medical Laboratory Technology, 6(2). https://doi.org/10.33084/bjmlt.v6i2.7093
Pramono, A., Inayati, A., & Kesumadewi, T. (2021). Pengaruh Penerapan Terapi Murottal Terhadap Penurunan Nyeri Pada Pasien Post Op Appendiktomi Di Kota Metro. Jurnal Cendikia Muda, 4(1), 452–456.
None Fenna Ayuningtyas, Ani, F., & None Rina Prawati. (2024). Case Report: Pengaruh Stimulasi Taktil-Kinestetik dan murotal Al Quran terhadap Respirasi, Saturasi Oksigen dan Heart Rate pada Neonatal Respiratory Distress di Ruang PICU/NICU RSUD TJITROWARDOJO. Deleted Journal, 2(2), 107–116. https://doi.org/10.61132/corona.v2i2.405
Majidipour, N., Nirouzad, F., Madmoli, Y., Sarrafzade, S., Kalani, L., Aghababaeian, H., & Borujeni, S. (2018). The Effect of Holy Quran Recitation on the Physiological Responses of Premature Infants during Phlebotomy: A Randomized Clinical Trial. Int J Pediatr, 6(7). https://doi.org/10.22038/ijp.2017.24203.2038
Amalu, C., Maftuchah, M., & Ulya, F. H. (2022). Pengaruh Terapi Murrotal Al-Qur’an terhadap Kualitas Tidur Bayi Usia 3-6 Bulan. Window of Midwifery Journal, 24–30. https://doi.org/10.33096/wom.vi.332
Williams, M. D., & Lascelles, B. D. X. (2020). Early Neonatal Pain—A Review of Clinical and Experimental Implications on Painful Conditions Later in Life. Frontiers in Pediatrics, 8(30). https://doi.org/10.3389/fped.2020.00030
Hanson, A., & Burrell, B. D. (2018). Are the Persistent Effects of “Gate Control” Stimulation on Nociception a Form of Generalization of Habituation that is Endocannabinoid-Dependent?. Neurobiology of Learning and Memory, 155, 361–370. https://doi.org/10.1016/j.nlm.2018.09.001
Sprouse-Blum, A. S., Smith, G., Sugai, D., & Parsa, F. D. (2010). Understanding endorphins and their importance in pain management. Hawaii Medical Journal, 69(3), 70–71. https://pubmed.ncbi.nlm.nih.gov/20397507/
Zieglgänsberger, W. (2019). Substance P and pain chronicity. Cell and Tissue Research, 375(1), 227–241. https://doi.org/10.1007/s00441-018-2922-y
Qiu, J., Jiang, Y., Li, F., Tong, Q., Rong, H., & Cheng, R. (2017). Effect of combined music and touch intervention on pain response and β-endorphin and cortisol concentrations in late preterm infants. BMC Pediatrics, 17. https://doi.org/10.1186/s12887-016-0755-y
Shah, S. R., Kadage, S., & Sinn, J. (2017). Trial of Music, Sucrose, and Combination Therapy for Pain Relief during Heel Prick Procedures in Neonates. The Journal of Pediatrics, 190, 153-158.e2. https://doi.org/10.1016/j.jpeds.2017.08.003
Asadi-Noghabi, F., Tavassoli-Farahi, M., Yousefi, H., & Sadeghi, T. (2014). Neonate Pain Management: What do Nurses Really Know? Global Journal of Health Science, 6(5).
https://doi.org/10.5539/gjhs.v6n5p284
Krishnan, L. (2013). Pain Relief in Neonates. Journal of Neonatal Surgery, 2(2), 19. https://doi.org/10.47338/jns.v2.31
Thiviya Selvanathan, Ufkes, S., Guo, T., Chau, V., Branson, H. M., Ibrahim, G. M., Ly, L. G., Kelly, E. N., Grunau, R. E., & Miller, S. P. (2024). Pain Exposure
and Brain Connectivity in Preterm Infants. JAMA Network Open, 7(3), e242551–e242551. https://doi.org/10.1001/jamanetworkopen.2024.2551
Campbell, T. S., Johnson, J. A., & Zernicke, K. A. (2020). Gate control theory of pain. Encyclopedia of Behavioral Medicine, 1(1), 914–916. https://doi.org/10.1007/978-3-030-39903-0_113
Published
2025-05-31
Section
Articles
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